Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants
نویسندگان
چکیده
منابع مشابه
Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants.
Very high-throughput sequencing technologies need to be matched by high-throughput functional studies if we are to make full use of the current explosion in genome sequences. We have generated a very large bacterial mutant pool, consisting of an estimated 1.1 million transposon mutants and we have used genomic DNA from this mutant pool, and Illumina nucleotide sequencing to prime from the trans...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2009
ISSN: 1088-9051
DOI: 10.1101/gr.097097.109